ACR-Modified Keyhole-Lympet Hemocyanine 抗体
IHC
宿主: 小鼠
Monoclonal
5F6
unconjugated
1 image
(1 reference)-
- 抗原
- ACR-Modified Keyhole-Lympet Hemocyanine
- 宿主
- 小鼠
- 克隆类型
- 单克隆
- 应用范围
- Immunohistochemistry (IHC)
- 特异性
- Specific for ACR-modified protein (especially FDP-lysine type derivative).
- 纯化方法
- Protein A purified
- 克隆位点
- 5F6
- 亚型
- IgG1 kappa
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- 应用备注
- Recommended antibody concentration is 0.5-1.0 µg/mL on paraformaldehyde fixed tissue.
- 限制
- 仅限研究用
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- 状态
- Frozen
- 缓冲液
- 100 µg/mL antibody in 10mM PBS containing 0.1% NaN3 and 0.5% BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "Expressions of lipid oxidation markers, N(ε)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity in rats." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 73, Issue 6, pp. 821-6, (2011) (PubMed).
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: "Expressions of lipid oxidation markers, N(ε)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity in rats." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 73, Issue 6, pp. 821-6, (2011) (PubMed).
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- 抗原
- ACR-Modified Keyhole-Lympet Hemocyanine
- 背景
- Acrolein (ACR) is a representative carcinogenic aldehyde found ubiquitously in the environment and formed endogenously through oxidation reactions, such as lipid peroxidation and myeloperoxidasecatalyzed amino acid oxidation. ACR is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with ACR and lysine residue leads to the formation of numerous numbers of adducts, such as formyl-dehydropiperidino-lysine (FDP-lysine) type derivative. This antibody is specific for the ACR-modified protein, especially FDP-lysine type derivative.
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