Ankyrin G 抗体
(Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats\; a central region with a highly conserved spectrin binding domain\; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
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Ankyrin G 抗体
High quality antibodies with extensive validation data.
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Latest Publications for our Ankyrin G Products
: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).: "Acceleration of conduction velocity linked to clustering of nodal components precedes myelination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 3, pp. E321-8, (2015) (PubMed).
: "A distinct subtype of dopaminergic interneuron displays inverted structural plasticity at the axon initial segment." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 4, pp. 1573-90, (2015) (PubMed).
: "Axon initial segment-associated microglia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 5, pp. 2283-92, (2015) (PubMed).
: "Preferential targeting of Nav1.6 voltage-gated Na+ Channels to the axon initial segment during development." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124397, (2015) (PubMed).
: "CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment." in: Journal of neurochemistry, Vol. 134, Issue 3, pp. 527-37, (2015) (PubMed).
: "Impact of preconditioning with retinoic acid during early development on morphological and functional characteristics of human induced pluripotent stem cell-derived neurons." in: Stem cell research, Vol. 15, Issue 1, pp. 30-41, (2015) (PubMed).
: "A recurrent KCNQ2 pore mutation causing early onset epileptic encephalopathy has a moderate effect on M current but alters subcellular localization of Kv7 channels. ..." in: Neurobiology of disease, Vol. 80, pp. 80-92, (2015) (PubMed).
: "Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 21, pp. 8359-75, (2015) (PubMed).
: "Exon organization and novel alternative splicing of Ank3 in mouse heart." in: PLoS ONE, Vol. 10, Issue 5, pp. e0128177, (2015) (PubMed).
Synonyms and alternative names related to Ankyrin G
ankyrin 3 (ANK3), ankyrin 3 (legA6), ankyrin 3 (PB000272.02.0), ankyrin 3 (PY00018), ankyrin 3, node of Ranvier (ankyrin G) (ANK3), ankyrin 3, node of Ranvier (ankyrin G) (ank3), ankyrin 3 (ank3), ankyrin 3, epithelial (Ank3), 2900054D09Rik, AI314020, Ank-3, ANK3, AnkG, Ankyrin-3, ankyrin-G, Ankyrin-G, ANKYRIN-GProtein level used designations for Ankyrin G
- ankyrin 3
- ankyrin 3, node of Ranvier (ankyrin G)
- ankyrin-3
- ankyrin 3, node of Ranvier (ankyrin G)-like
- ankyrin-3-like
- brain-specific ankyrin-G
- ankyrin G119
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