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ANKH 产品

(Ankylosis, Progressive Homolog (Mouse) (ANKH))

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This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008].

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Featured ANKH Categories

ANKH 抗体

High quality antibodies with extensive validation data.

ANKH 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ANKH 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
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  • (4)
Cat. No. ABIN653697
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7264924
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, FACS, IHC (p)
Validations
  • (2)
Cat. No. ABIN1892978
Quantity 200 μL
Datasheet Datasheet

Recommended ANKH 蛋白

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Reactivity
Source
Validations
Cat. No.
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Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1345071
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3107094
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3130021
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ANKH Products

Williams: "Familial calcium pyrophosphate dihydrate deposition disease and the ANKH gene." in: Current opinion in rheumatology, Vol. 15, Issue 3, pp. 326-31, (2003) (PubMed).

Nelson, Clegg, Arnold, Ferguson, Bonham, White, Hood, Lin: "The program of androgen-responsive genes in neoplastic prostate epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 18, pp. 11890-5, (2002) (PubMed).

Williams, Zhang, Timms, Bonavita, Caeiro, Broxholme, Cuthbertson, Jones, Marchegiani, Reginato, Russell, Wordsworth, Carr, Brown: "Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH." in: American journal of human genetics, Vol. 71, Issue 4, pp. 985-91, (2002) (PubMed).

Reichenberger, Tiziani, Watanabe, Park, Ueki, Santanna, Baur, Shiang, Grange, Beighton, Gardner, Hamersma, Sellars, Ramesar, Lidral, Sommer, Raposo do Amaral, Gorlin, Mulliken, Olsen: "Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANK." in: American journal of human genetics, Vol. 68, Issue 6, pp. 1321-6, (2001) (PubMed).

Nürnberg, Thiele, Chandler, Höhne, Cunningham, Ritter, Leschik, Uhlmann, Mischung, Harrop, Goldblatt, Borochowitz, Kotzot, Westermann, Mundlos, Braun, Laing, Tinschert: "Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia." in: Nature genetics, Vol. 28, Issue 1, pp. 37-41, (2001) (PubMed).

Ho, Johnson, Kingsley: "Role of the mouse ank gene in control of tissue calcification and arthritis." in: Science (New York, N.Y.), Vol. 289, Issue 5477, pp. 265-70, (2000) (PubMed).

Synonyms and alternative names related to ANKH

ANKH inorganic pyrophosphate transport regulator (ANKH), ANKH inorganic pyrophosphate transport regulator (Ankh), progressive ankylosis (Ank), ANKH inorganic pyrophosphate transport regulator b (ankhb), ANKH inorganic pyrophosphate transport regulator S homeolog (ankh.S), ANKH inorganic pyrophosphate transport regulator a (ankha), ANK, Ank, ank, Ankh, ankh, CCAL2, CMDJ, CPPDD, D15Ertd221e, HANK, MANK, mKIAA1581, wu:fc08d03, wu:fj64g09, zgc:110290

Protein level used designations for ANKH

  • ankylosis, progressive homolog
  • progressive ankylosis protein homolog
  • progressive ankylosis homolog
  • progressive ankylosis protein
  • ankylosis, progressive homolog (mouse)
  • progressive ankylosis protein homolog-like
  • fn54 protein
  • ANK-B
  • progressive ankylosis protein homolog B
  • progressive ankylosis-like protein
  • ankylosis, progressive homolog a
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