ANGPTL4 产品
(Angiopoietin-Like 4 (ANGPTL4))
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This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Jul 2008].
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Featured ANGPTL4 Categories
ANGPTL4 抗体
High quality antibodies with extensive validation data.
ANGPTL4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ANGPTL4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ANGPTL4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7433018
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7433021
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (4)
Cat. No.
ABIN526478
Quantity
50 μg
Datasheet
Datasheet
Recommended ANGPTL4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6720566
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6961997
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6953728
Quantity
96 tests
Datasheet
Datasheet
Recommended ANGPTL4 蛋白
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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273833
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7273832
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (2)
- (1)
Cat. No.
ABIN1794453
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ANGPTL4 Products
: "Interaction of Gut Microbiota and High-Sodium, Low-Potassium Diet in Altering Plasma Triglyceride Profiles Revealed by Lipidomics Analysis." in: Molecular nutrition & food research, Vol. 63, Issue 24, pp. e1900752, (2020) (PubMed).: "The association of angiopoietin-like peptide 4 levels with obesity and hepatosteatosis in adolescents." in: Cytokine, Vol. 125, pp. 154802, (2020) (PubMed).
: "The downregulation of ANGPTL4 inhibits the migration and proliferation of tongue squamous cell carcinoma." in: Archives of oral biology, Vol. 71, pp. 144-149, (2017) (PubMed).
: "Angiopoietin-Like-4, a Potential Target of Tacrolimus, Predicts Earlier Podocyte Injury in Minimal Change Disease." in: PLoS ONE, Vol. 10, Issue 9, pp. e0137049, (2015) (PubMed).
: "Upregulation of podocyte-secreted angiopoietin-like-4 in diabetic nephropathy." in: Endocrine, Vol. 49, Issue 2, pp. 373-84, (2015) (PubMed).
: "Establishment of monoclonal HCC cell lines with organ site-specific tropisms." in: BMC cancer, Vol. 15, pp. 678, (2015) (PubMed).
: "Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy." in: Journal of hematology & oncology, Vol. 8, pp. 64, (2015) (PubMed).
: "Examination of angiopoietin-like protein 4, neuropeptide Y, omentin-1 levels of obese and non-obese patients with polycystic ovary syndrome." in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, Vol. 31, Issue 11, pp. 903-6, (2015) (PubMed).
: "Non-esterified fatty acids promote expression and secretion of angiopoietin-like protein 4 in calf hepatocytes cultured in vitro." in: Molecular and cellular biochemistry, (2014) (PubMed).
: "Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 11, pp. E1043-52, (2014) (PubMed).
Synonyms and alternative names related to ANGPTL4
angiopoietin like 4 (ANGPTL4), angiopoietin-like 4 (Angptl4), angiopoietin-like 4 (angptl4), ANGPTL2, ANGPTL4, ARP4, Arp4, Bk89, FIAF, Fiaf, fiaf, HFARP, Hfarp, im:7144703, Ng27, NL2, PGAR, Pgar, Pgarg, pp1158, Pp1158, si:rp71-39b20.7Protein level used designations for ANGPTL4
- PPARG angiopoietin related protein
- angiopoietin-like protein 4
- angiopoietin-related protein 4
- fasting-induced adipose factor
- hepatic angiopoietin-related protein
- hepatic fibrinogen/angiopoietin-related protein
- peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein
- 425O18-1
- fibrinogen/angiopoietin-related protein
- major histocompatibility complex region NG27
- secreted protein Bk89
- HFARP
- PPARG angiopoietin-related protein
- angiopoietin-like 4
- angiopoietin-like secreted glycoprotein 4
- angiopoietin-related protein 4-like
- angiopoietin-like 4 protein
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