Androgen Receptor 抗体
(Androgen Receptor (AR))
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
recommended
recommended
Androgen Receptor 抗体 (N-Term) (ABIN2857043)
AR 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
recommended
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Popular Androgen Receptor 抗体
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Cat. No.
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Human, Mouse, Rat
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WB, IHC, IF, ICC
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- (5)
- (1)
Cat. No.
ABIN1871059
Quantity
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Reactivity
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Application
WB, IF, IHC (p), ICC
Validations
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Cat. No.
ABIN2857043
Quantity
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WB, ELISA, IHC
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Cat. No.
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Cat. No.
ABIN7303750
Quantity
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Application
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Cat. No.
ABIN7427894
Quantity
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Cat. No.
ABIN559913
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Cat. No.
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Quantity
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Datasheet
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ABIN7433333
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Cat. No.
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Quantity
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IHC (p), IF (p)
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Cat. No.
ABIN730123
Quantity
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Cat. No.
ABIN7477375
Quantity
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Reactivity
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Quantity
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Datasheet
Datasheet
Latest Publications for our Androgen Receptor 抗体
: "Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats." in: Scientific reports, Vol. 8, Issue 1, pp. 490, (2018) (PubMed).: "Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer." in: European journal of medicinal chemistry, Vol. 152, pp. 542-559, (2018) (PubMed).
: "Influence of endocrine therapy on the ratio of androgen receptor (AR) to estrogen receptor (ER) positive circulating epithelial tumor cells (CETCs) in breast cancer." in: Journal of translational medicine, Vol. 16, Issue 1, pp. 356, (2018) (PubMed).
: "Effects of low dose of bisphenol A on the proliferation and mechanism of primary cultured prostate epithelial cells in rodents." in: Oncology letters, Vol. 14, Issue 3, pp. 2635-2642, (2017) (PubMed).
: "Targeting mTOR and p53 Signaling Inhibits Muscle Invasive Bladder Cancer In Vivo." in: Cancer prevention research (Philadelphia, Pa.), Vol. 9, Issue 1, pp. 53-62, (2016) (PubMed).
: "Yangjing Capsule Ameliorates Spermatogenesis in Male Mice Exposed to Cyclophosphamide." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 980583, (2016) (PubMed).
: "Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial cells exposed to subchronic testosterone." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1361-1366, (2016) (PubMed).
: "Elevated expression levels of androgen receptors and matrix metalloproteinase-2 and -9 in 30 cases of hepatocellular carcinoma compared with adjacent tissues as predictors of cancer invasion and ..." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 905-908, (2015) (PubMed).
: "Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model." in: Oncology letters, Vol. 10, Issue 3, pp. 1819-1825, (2015) (PubMed).
: "Androgen receptor phosphorylation at serine 308 and serine 791 predicts enhanced survival in castrate resistant prostate cancer patients." in: International journal of molecular sciences, Vol. 14, Issue 8, pp. 16656-71, (2013) (PubMed).
Aliases for Androgen Receptor 抗体
androgen receptor (AR) 抗体androgen receptor (Ar) 抗体
androgen receptor (ar) 抗体
AIS 抗体
Andr 抗体
AR 抗体
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