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ANAPC4 产品

(Anaphase Promoting Complex Subunit 4 (ANAPC4))

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A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. [provided by RefSeq, Jul 2008].

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Featured ANAPC4 Categories

ANAPC4 抗体

High quality antibodies with extensive validation data.

ANAPC4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ANAPC4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN526177
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
Cat. No. ABIN6991324
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
Cat. No. ABIN7510297
Quantity 50 μg
Datasheet Datasheet

Recommended ANAPC4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345036
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088991
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136795
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ANAPC4 Products

De, Grubb, Zalenski, Pfaff, Pal, Majumder, Summers, Venere: "Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/CCDH1 Activity and Pharmacologic Inhibition of APC/CCDH1/CDC20 Compromises Viability." in: Molecular cancer research : MCR, Vol. 17, Issue 7, pp. 1519-1530, (2019) (PubMed).

Guan, Liu, Cai, Liu, Ye, Li, Li: "Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 11, pp. 1858-66, (2011) (PubMed).

Synonyms and alternative names related to ANAPC4

anaphase promoting complex subunit 4 (Anapc4), anaphase promoting complex subunit 4 L homeolog (anapc4.L), anaphase promoting complex subunit 4 (ANAPC4), anaphase promoting complex subunit 4 (anapc4), Transducin/WD40 repeat-like superfamily protein (APC4), 2610306D21Rik, ANAPC4, APC4, D5Ertd249e, DDBDRAFT_0186409, DDBDRAFT_0234268, DDB_0186409, DDB_0234268, F18E5.150, F18E5_150, MGC81278

Protein level used designations for ANAPC4

  • anaphase-promoting complex subunit 4
  • anaphase promoting complex subunit 4
  • Cyclosome subunit 4
  • cyclosome subunit 4
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