AMPK alpha 产品
(SNF1A/AMP-Activated Protein Kinase (SNF1A))
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The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008].
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Featured AMPK alpha Categories
AMPK alpha 抗体
High quality antibodies with extensive validation data.
AMPK alpha ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended AMPK alpha 抗体
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Recommended AMPK alpha ELISA试剂盒
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Latest Publications for our AMPK alpha Products
: "Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation." in: The EMBO journal, Vol. 39, Issue 7, pp. e103304, (2020) (PubMed).: "miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway." in: Oncotarget, Vol. 8, Issue 20, pp. 32566-32575, (2018) (PubMed).
: "Anti-osteoporosis activity of Sanguinarine in preosteoblast MC3T3-E1 cells and an ovariectomized rat model." in: Journal of cellular physiology, Vol. 233, Issue 6, pp. 4626-4633, (2018) (PubMed).
: "Diallyl Disulfide Inhibits Breast Cancer Stem Cell Progression and Glucose Metabolism by Targeting CD44/PKM2/AMPK Signaling." in: Current cancer drug targets, Vol. 18, Issue 6, pp. 592-599, (2018) (PubMed).
: "Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis." in: Journal of virology, Vol. 92, Issue 8, (2018) (PubMed).
: "Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance." in: Obesity research & clinical practice, Vol. 12, Issue 2, pp. 167-173, (2018) (PubMed).
: "Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
: "Maternal serum AMP-activated protein kinase levels in mild and severe preeclampsia." in: The journal of maternal-fetal & neonatal medicine, pp. 1-6, (2018) (PubMed).
: "High expressions of LDHA and AMPK as prognostic biomarkers for breast cancer." in: Breast (Edinburgh, Scotland), Vol. 30, pp. 39-46, (2017) (PubMed).
: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).
Synonyms and alternative names related to AMPK alpha
protein kinase AMP-activated catalytic subunit alpha 2 (PRKAA2), AMPK, AMPK2, AMPKa2, PRKAAProtein level used designations for AMPK alpha
- 5'-AMP-activated protein kinase catalytic subunit alpha-2
- 5'-AMP-activated protein kinase, catalytic alpha-2 chain
- ACACA kinase
- AMPK subunit alpha-2
- AMPK-alpha-2 chain
- HMGCR kinase
- acetyl-CoA carboxylase kinase
- hydroxymethylglutaryl-CoA reductase kinase
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