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AMACR 产品

(alpha-Methylacyl-CoA Racemase (AMACR))
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011].

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Featured AMACR Categories

AMACR 抗体

High quality antibodies with extensive validation data.

AMACR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

AMACR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AMACR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, StM
Validations
  • (7)
Cat. No. ABIN6939431
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, StM
Validations
  • (5)
Cat. No. ABIN6939430
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN3021498
Quantity 100 μL
Datasheet Datasheet

Recommended AMACR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964773
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953651
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN4993314
Quantity 96 tests
Datasheet Datasheet

Recommended AMACR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121802
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344965
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409431
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AMACR Products

Drusian, Nigro, Mannella, Pagliarini, Pema, Costa, Benigni, Larcher, Chiaravalli, Gaude, Montorsi, Capitanio, Musco, Frezza, Boletta: "mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma." in: Cell reports, Vol. 24, Issue 5, pp. 1093-1104.e6, (2018) (PubMed).

Wang, Tian, Xiao, Zhang, Sun, Tang: "A metanephric adenoma of the kidney associated with polycythemia: A case report." in: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).

Chen, Watson, Marengo, Decker, Coleman, Nelson, Sikes: "Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo." in: Cancer letters, Vol. 244, Issue 2, pp. 274-88, (2006) (PubMed).

Epstein, Herawi: "Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care." in: The Journal of urology, Vol. 175, Issue 3 Pt 1, pp. 820-34, (2006) (PubMed).

Ferdinandusse, Denis, Clayton, Graham, Rees, Allen, McLean, Brown, Vreken, Waterham, Wanders: "Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy." in: Nature genetics, Vol. 24, Issue 2, pp. 188-91, (2000) (PubMed).

Kotti, Savolainen, Helander, Yagi, Novikov, Kalkkinen, Conzelmann, Hiltunen, Schmitz: "In mouse alpha -methylacyl-CoA racemase, the same gene product is simultaneously located in mitochondria and peroxisomes." in: The Journal of biological chemistry, Vol. 275, Issue 27, pp. 20887-95, (2000) (PubMed).

Synonyms and alternative names related to AMACR

alpha-methylacyl-CoA racemase (AMACR), alpha-methylacyl-CoA racemase (mcr), PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) (mcr), alpha-methylacyl-CoA racemase (BPSL0064), Alpha-methylacyl-CoA racemase (Maqu_2037), alpha-methylacyl-CoA racemase (UREG_03852), alpha-methylacyl-CoA racemase (MCYG_01809), alpha-methylacyl-CoA racemase (amacr), alpha-methylacyl-CoA racemase L homeolog (amacr.L), alpha-methylacyl-CoA racemase (MGYG_04259), alpha-methylacyl-CoA racemase (NCU04099), alpha-methylacyl-CoA racemase (Amacr), AMACR, amacr, AMACRD, CBAS4, Da1-8, DKFZp469O1232, Macr1, Marc1, MGC89832, NCU04099.1, RACE, RM

Protein level used designations for AMACR

  • alpha-methylacyl-CoA racemase
  • Alpha-methylacyl-CoA racemase
  • alpha-methylacyl-CoA racemase-like
  • amacr protein
  • 2-methylacyl-CoA racemase
  • 2-arylpropionyl-CoA epimerase
  • alpha-methylacyl-Coenzyme A racemase
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