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ALT 产品

(Alanine Aminotransferase (ALT))

Categories

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1)\; also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009].

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Featured ALT Categories

ALT 抗体

High quality antibodies with extensive validation data.

ALT ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ALT 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ALT 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (11)
Cat. No. ABIN7438472
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (6)
Cat. No. ABIN7429409
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7429412
Quantity 100 μL
Datasheet Datasheet

Recommended ALT ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (5)
Cat. No. ABIN6730944
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
Cat. No. ABIN6730902
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN6953568
Quantity 96 tests
Datasheet Datasheet

Recommended ALT 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7194188
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355674
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121760
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our ALT Products

Mousa, Soliman, Alhumaydhi, Almatroudi, Al Rugaie, Allemailem, Alrumaihi, Khan, Rezk, Aljasir, Alwashmi, Aba Alkhayl, Albutti, Seleem: "Garlic Extract Alleviates Trastuzumab-Induced Hepatotoxicity in Rats Through Its Antioxidant, Anti-Inflammatory, and Antihyperlipidemic Effects." in: Journal of inflammation research, Vol. 14, pp. 6305-6316, (2021) (PubMed).

Wang, Kaufmann, Engleitner, Lu, Mogler, Olsavszky, Öllinger, Zhong, Geraud, Cheng, Rad, Schmid, Friess, Hüser, Hartmann, von Figura: "Brg1 promotes liver regeneration after partial hepatectomy via regulation of cell cycle." in: Scientific reports, Vol. 9, Issue 1, pp. 2320, (2020) (PubMed).

Tao, Chen, Wang, Chen, Zhao, Zheng, Yang: "CD47 Deficiency in Mice Exacerbates Chronic Fatty Diet-Induced Steatohepatitis Through Its Role in Regulating Hepatic Inflammation and Lipid Metabolism." in: Frontiers in immunology, Vol. 11, pp. 148, (2020) (PubMed).

Wang, Xue, Li, Yang, He, Zhang, Zhang, Tang: "In Vivo Two-Photon Fluorescence Imaging of the Activity of the Inflammatory Biomarker LTA4H in a Mouse Pneumonia Model." in: Analytical chemistry, Vol. 90, Issue 10, pp. 6020-6027, (2019) (PubMed).

Xiahou, Wang, Shen, Zhu, Xu, Hu, Guo, Li, Tian, Liu, Liang: "NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury." in: Nature communications, Vol. 8, Issue 1, pp. 950, (2018) (PubMed).

Li, Lu, Liu, Liang, Wang, Wang, Li, Yao, Zhang, Wen, Zhang, Li, Lv, He, Guo, Guan, Yu, Dang, Wu, Li, Chen, Jiang, Sun, Zhang, Lu, Zhang: "A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer." in: Nature communications, Vol. 8, Issue 1, pp. 1390, (2018) (PubMed).

Xie, He, Wang, Xiao, Zhou, Du, Xue, Wang: "Lactulose attenuates METH-induced neurotoxicity by alleviating the impaired autophagy, stabilizing the perturbed antioxidant system and suppressing apoptosis in rat striatum." in: Toxicology letters, Vol. 289, pp. 107-113, (2018) (PubMed).

Chung, Chen, Yu, Lee, Song, Choe, Lee, Kim, Hong: "A critical role of hepatitis B virus polymerase in cirrhosis, hepatocellular carcinoma, and steatosis." in: FEBS open bio, Vol. 8, Issue 1, pp. 130-145, (2018) (PubMed).

Feng, Wang, Zhang, Gao, Tao, Ge, Zhu, Bi: "Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats." in: Biochimica et biophysica acta, Vol. 1861, Issue 7, pp. 1801-1812, (2017) (PubMed).

Samuelson, Shellito, Maffei, Tague, Campagna, Blanchard, Luo, Taylor, Ronis, Molina, Welsh: "Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006426, (2017) (PubMed).

Synonyms and alternative names related to ALT

glutamic--pyruvic transaminase (GPT), glutamic-pyruvate transaminase (alanine aminotransferase) (GPT), glutamic--pyruvic transaminase (Gpt), alanine aminotransferase (Tb927.1.3950), alanine aminotransferase (ANI_1_368094), alanine aminotransferase (AOR_1_284154), alanine aminotransferase (ALAT_1), alanine aminotransferase 1 (ALAAT1), alanine aminotransferase (EHI_159710), alanine aminotransferase (EHI_096750), alanine aminotransferase 1 (LOC5572541), alanine aminotransferase (ALAT), alanine aminotransferase (AAT2), glutamic pyruvic transaminase, soluble (Gpt), dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (Dpagt1), alanine aminotransferase 2-like (LOC100537633), Alanine aminotransferase 1, mitochondrial (AlaAT1), 24.t00016, 233.t00009, 1300007J06Rik, 2310022B03Rik, AAT1, ALANINE AMINOTRANSFERAS, alanine aminotransferas, ALT, ALT1, An11g02620, AO090003000164, AtAlaAT1, AtAlaATc, AU021132, Dpagt2, Gnpta, GPT, gpt, Gpt-1, GPT1, Gpt1, T13M22.3, T13M22_3

Protein level used designations for ALT

  • GPT 1
  • alanine aminotransferase 1
  • glutamate pyruvate transaminase 1
  • glutamic--alanine transaminase 1
  • glutamic--pyruvic transaminase 1
  • glutamic-alanine transaminase 1
  • glutamic-pyruvate transaminase (alanine aminotransferase)
  • ALT1
  • glutamic pyruvate transaminase
  • glutamic pyruvic transaminase (alanine aminotrasferase)
  • glutamic pyruvic transaminase 1, soluble
  • alanine aminotransferase
  • alanine aminotransferase 1-like
  • G1PT
  • N-acetylglucosamine-1-phosphate transferase
  • UDP-N-acetylglucosamine lysosomal enzyme N-acetylglucosamine phosphotransferase
  • UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
  • dolichyl-phosphate alpha-N-acetylglucosaminephosphotransferase 2
  • glcNAc-1-P transferase
  • glutamic pyruvic transaminase, soluble
  • alanine aminotransferase 2-like
  • glutamic--pyruvic transaminase
  • Alanine-2-oxoglutarate aminotransferase 4
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