ALS2 抗体
(Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
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ALS2 抗体 by Grade
Find ALS2 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
ALS2 抗体 by 适用
Find ALS2 抗体 for a variety of species such as anti-Human ALS2, anti-Mouse ALS2, anti-Rat ALS2. The species listed below are among those available. Click on a link to go to the corresponding products.
ALS2 抗体 by 应用范围
Find ALS2 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
ALS2 抗体 by 抗体来源
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ALS2 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ALS2 抗体. Click on a link to go to the corresponding products.
ALS2 抗体 by 克隆
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Popular ALS2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6136830
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7143956
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN528269
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IF
Validations
- (1)
Cat. No.
ABIN7010503
Quantity
60 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN528268
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1327365
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN6259903
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN184691
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6743275
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN390394
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
Cat. No.
ABIN1387647
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1392877
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1392873
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN2809666
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1392875
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our ALS2 抗体
: "Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria." in: eLife, Vol. 7, (2018) (PubMed).: "Are alsin and spartin novel interaction partners?" in: Biochemical and biophysical research communications, Vol. 427, Issue 1, pp. 1-4, (2012) (PubMed).
: "The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis." in: Nature genetics, Vol. 29, Issue 2, pp. 160-5, (2001) (PubMed).
Aliases for ALS2 抗体
amyotrophic lateral sclerosis 2a (juvenile) (als2a) 抗体alsin (CpipJ_CPIJ008258) 抗体
alsin (CpipJ_CPIJ008260) 抗体
ALS2, alsin Rho guanine nucleotide exchange factor (ALS2) 抗体
ALS2, alsin Rho guanine nucleotide exchange factor (Als2) 抗体
amyotrophic lateral sclerosis 2 (juvenile) (Als2) 抗体
amyotrophic lateral sclerosis 2 (juvenile) (ALS2) 抗体
3222402C23Rik 抗体
9430073A21Rik 抗体
als2 抗体
ALS2CR6 抗体
Als2cr6 抗体
Alsin 抗体
ALSJ 抗体
IAHSP 抗体
mKIAA1563 抗体
PLSJ 抗体
si:dkey-33m14.1 抗体
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