ALS2 产品
(Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))
Categories
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured ALS2 Categories
ALS2 抗体
High quality antibodies with extensive validation data.
Recommended ALS2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6136830
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7143956
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN528269
Quantity
100 μg
Datasheet
Datasheet
Recommended ALS2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344948
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ALS2 Products
: "Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria." in: eLife, Vol. 7, (2018) (PubMed).: "Are alsin and spartin novel interaction partners?" in: Biochemical and biophysical research communications, Vol. 427, Issue 1, pp. 1-4, (2012) (PubMed).
: "The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis." in: Nature genetics, Vol. 29, Issue 2, pp. 160-5, (2001) (PubMed).
Synonyms and alternative names related to ALS2
amyotrophic lateral sclerosis 2a (juvenile) (als2a), alsin (CpipJ_CPIJ008258), alsin (CpipJ_CPIJ008260), ALS2, alsin Rho guanine nucleotide exchange factor (ALS2), ALS2, alsin Rho guanine nucleotide exchange factor (Als2), amyotrophic lateral sclerosis 2 (juvenile) (Als2), amyotrophic lateral sclerosis 2 (juvenile) (ALS2), 3222402C23Rik, 9430073A21Rik, als2, ALS2CR6, Als2cr6, Alsin, ALSJ, IAHSP, mKIAA1563, PLSJ, si:dkey-33m14.1Protein level used designations for ALS2
- alsin 2
- amyotrophic lateral sclerosis 2 (juvenile)
- alsin
- alsin-like
- amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein
- amyotrophic lateral sclerosis 2 protein
- amyotrophic lateral sclerosis 2 protein homolog
- amyotrophic lateral sclerosis protein 2 homolog
- amyotrophic lateral sclerosis 2 (juvenile) homolog
您还需要查找其他产品吗？
- ALR2
- ALPPL2
- ALPL
- ALPK3
- ALPK2
- ALPK1
- alphaHBDH
- alpha-Trichosanthin
- alpha-Thrombin
- alpha-N-Acetylgalactosaminide alpha-2,6-Sialyltransferase 3
- alpha-Mannosidase II
- alpha-L-Fucosidase
- alpha-Endorphin
- Alpha-amylase 1
- alpha-1,4-Glucan-Protein Synthase
- alpha Tubulin
- alpha Taxilin
- alpha KGDHC
- alpha Fetoprotein
- alpha Adducin
You are here:
