ALK 抗体
(Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))
This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)\\/EML4 (chromosome 2), ALK\\/RANBP2 (chromosome 2), ALK\\/ATIC (chromosome 2), ALK\\/TFG (chromosome 3), ALK\\/NPM1 (chromosome 5), ALK\\/SQSTM1 (chromosome 5), ALK\\/KIF5B (chromosome 10), ALK\\/CLTC (chromosome 17), ALK\\/TPM4 (chromosome 19), and ALK\\/MSN (chromosome X).[provided by RefSeq, Jan 2011].
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ALK 抗体 by 适用
Find ALK 抗体 for a variety of species such as anti-Human ALK, anti-Mouse ALK. The species listed below are among those available. Click on a link to go to the corresponding products.
ALK 抗体 by 应用范围
Find ALK 抗体 validated for a specific application such as IHC (p), WB, ELISA, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.
ALK 抗体 by 抗体来源
Find ALK 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
ALK 抗体 by 抗原表位
Find ALK 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
ALK 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ALK 抗体. Click on a link to go to the corresponding products.
ALK 抗体 by 克隆
Find ALK 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular ALK 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC (p), WB
Validations
- (2)
Cat. No.
ABIN6243477
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p)
Validations
- (1)
- (1)
Cat. No.
ABIN6243478
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p)
Validations
- (1)
- (1)
Cat. No.
ABIN6243476
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN3029939
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6243474
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN6243479
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3029935
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p)
Validations
Cat. No.
ABIN6654206
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p)
Validations
Cat. No.
ABIN6654203
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p)
Validations
Cat. No.
ABIN6654202
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC (p)
Validations
Cat. No.
ABIN6654208
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ALK 抗体
: "Anaplastic lymphoma kinase immunohistochemistry in lung adenocarcinomas: Evaluation of performance of standard manual method using D5F3 antibody." in: Indian journal of cancer, Vol. 54, Issue 1, pp. 209-213, (2018) (PubMed).: "Clinicopathological analysis of epithelioid inflammatory myofibroblastic sarcoma." in: Oncology letters, Vol. 15, Issue 6, pp. 9317-9326, (2018) (PubMed).
: "Worse disease-free, tumor-specific, and overall survival in surgically-resected lung adenocarcinoma patients with ALK rearrangement." in: Oncotarget, Vol. 8, Issue 49, pp. 86066-86081, (2017) (PubMed).
: "Crizotinib reduces the rate of dark adaptation in the rat retina independent of ALK inhibition." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 116-25, (2016) (PubMed).
: "A novel, highly sensitive ALK antibody 1A4 facilitates effective screening for ALK rearrangements in lung adenocarcinomas by standard immunohistochemistry." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 10, Issue 4, pp. 713-6, (2015) (PubMed).
: "Inflammatory myofibroblastic tumour of the bladder in children: A review." in: Journal of pediatric urology, (2015) (PubMed).
: "Extraordinary response to crizotinib in a woman with squamous cell lung cancer after two courses of failed chemotherapy." in: BMC pulmonary medicine, Vol. 14, pp. 83, (2014) (PubMed).
: "Biochemical and functional interaction between ZNF224 and ZNF255, two members of the Kruppel-like zinc-finger protein family and WT1 protein isoforms." in: Human molecular genetics, Vol. 19, Issue 18, pp. 3544-56, (2010) (PubMed).
: "Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1." in: Blood, Vol. 89, Issue 4, pp. 1394-404, (1997) (PubMed).
Aliases for ALK 抗体
anaplastic lymphoma kinase (Alk) 抗体anaplastic lymphoma receptor tyrosine kinase (ALK) 抗体
ALK receptor tyrosine kinase (ALK) 抗体
ALK receptor tyrosine kinase (Alk) 抗体
ALK 抗体
CD246 抗体
NBLST3 抗体
Tcrz 抗体
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