电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ALDH5A1 产品

(Aldehyde Dehydrogenase 5 Family, Member A1 (ALDH5A1))

Categories

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured ALDH5A1 Categories

ALDH5A1 抗体

High quality antibodies with extensive validation data.

ALDH5A1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ALDH5A1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ALDH5A1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7170921
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN521695
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN574091
Quantity 0.05 mg
Datasheet Datasheet

Recommended ALDH5A1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964705
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1159998
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1159999
Quantity 96 tests
Datasheet Datasheet

Recommended ALDH5A1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121776
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344840
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2127853
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our ALDH5A1 Products

Ippolito, Piwnica-Worms: "A fluorescence-coupled assay for gamma aminobutyric acid (GABA) reveals metabolic stress-induced modulation of GABA content in neuroendocrine cancer." in: PLoS ONE, Vol. 9, Issue 2, pp. e88667, (2014) (PubMed).

Joslyn, Ravindranathan, Brush, Schuckit, White: "Human variation in alcohol response is influenced by variation in neuronal signaling genes." in: Alcoholism, clinical and experimental research, Vol. 34, Issue 5, pp. 800-12, (2010) (PubMed).

Knerr, Pearl, Bottiglieri, Snead, Jakobs, Gibson et al.: "Therapeutic concepts in succinate semialdehyde dehydrogenase (SSADH; ALDH5a1) deficiency (gamma-hydroxybutyric aciduria). Hypotheses evolved from 25 years of patient evaluation, studies in Aldh5a1-/- ..." in: Journal of inherited metabolic disease, Vol. 30, Issue 3, pp. 279-94, (2007) (PubMed).

Blasi, Palmerio, Aiello, Rocchi, Malaspina, Novelletto: "SSADH variation in primates: intra- and interspecific data on a gene with a potential role in human cognitive functions." in: Journal of molecular evolution, Vol. 63, Issue 1, pp. 54-68, (2006) (PubMed).

Plomin, Turic, Hill, Turic, Stephens, Williams, Owen, ODonovan: "A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability." in: Molecular psychiatry, Vol. 9, Issue 6, pp. 582-6, (2004) (PubMed).

Synonyms and alternative names related to ALDH5A1

aldehyde dehydrogenase 5 family member A1 (ALDH5A1), aldehyde dehydrogenase 5 family member A1 (aldh5a1), aldehyde dehydrogenase 5 family, member A1 (Aldh5a1), aldhehyde dehydrogenase family 5, subfamily A1 (Aldh5a1), 6330403E24Rik, Ahd-1, Ahd1, D630032B01Rik, OTTMUSG00000000613, SSADH, Ssadh, SSDH, Ssdh1

Protein level used designations for ALDH5A1

  • NAD(+)-dependent succinic semialdehyde dehydrogenase
  • aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)
  • aldehyde dehydrogenase 5A1
  • aldehyde dehydrogenase family 5 member A1
  • succinate-semialdehyde dehydrogenase, mitochondrial
  • succinic semialdehyde dehydrogenase
  • aldehyde dehydrogenase 5 family, member A1
  • mitochondrial succinate semialdehyde dehydrogenase
  • aldehyde dehydrogenase family 5, subfamily A1
  • aldehyde dehydrogenase 1, mitochondrial
You are here:
客服