AKT1 产品
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
Categories
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011].
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Featured AKT1 Categories
AKT1 抗体
High quality antibodies with extensive validation data.
AKT1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
AKT1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AKT1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (3)
- (6)
Cat. No.
ABIN6136733
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7439390
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, IP
Validations
- (7)
Cat. No.
ABIN7167024
Quantity
100 μg
Datasheet
Datasheet
Recommended AKT1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN625220
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN625233
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6960408
Quantity
96 tests
Datasheet
Datasheet
Recommended AKT1 蛋白
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Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (3)
Cat. No.
ABIN5624568
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125673
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344778
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our AKT1 Products
: "Enforced expression of miR-92b blunts E. coli lipopolysaccharide-mediated inflammatory injury by activating the PI3K/AKT/β-catenin pathway via targeting PTEN." in: International journal of biological sciences, Vol. 17, Issue 5, pp. 1289-1301, (2022) (PubMed).: "ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer." in: Aging, Vol. 12, Issue 10, pp. 9915-9934, (2021) (PubMed).
: "SQSTM1/p62 Promotes Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer by Regulating the AKT/AMPK/mTOR Signaling Pathway." in: Frontiers in oncology, Vol. 11, pp. 638701, (2021) (PubMed).
: "Shaoyao-Gancao Decoction Ameliorates the Inflammation State in Polycystic Ovary Syndrome Rats via Remodeling Gut Microbiota and Suppressing the TLR4/NF-κB Pathway." in: Frontiers in pharmacology, Vol. 12, pp. 670054, (2021) (PubMed).
: "8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway." in: Frontiers in pharmacology, Vol. 12, pp. 711701, (2021) (PubMed).
: "The neuronal receptor tyrosine kinase Alk is a target for longevity." in: Aging cell, Vol. 19, Issue 5, pp. e13137, (2020) (PubMed).
: "Mouse model of metformin-induced diarrhea." in: BMJ open diabetes research & care, Vol. 8, Issue 1, (2020) (PubMed).
: "PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism." in: BMC molecular biology, Vol. 20, Issue 1, pp. 24, (2020) (PubMed).
: "Qigesan reduces the motility of esophageal cancer cells via inhibiting Gas6/Axl and NF-κB expression." in: Bioscience reports, Vol. 39, Issue 6, (2020) (PubMed).
: "Woodchuck VEGF (wVEGF) characteristics: Model for angiogenesis and human hepatocellular carcinoma directed therapies." in: Archives of biochemistry and biophysics, Vol. 661, pp. 97-106, (2019) (PubMed).
Synonyms and alternative names related to AKT1
AKT serine/threonine kinase 1 (AKT1), thymoma viral proto-oncogene 1 (Akt1), CG4006 gene product from transcript CG4006-RE (Akt1), actin beta (ACTB), AKT serine/threonine kinase 1 (Akt1), v-akt murine thymoma viral oncogene homolog 1 S homeolog (akt1.S), v-akt murine thymoma viral oncogene homolog 1 (akt1), AKT serine/threonine kinase 1 (akt1), K+ transporter 1 (KT1), Serine/threonine-protein kinase akt-1 (akt-1), ACT-5, AKT, Akt, akt, akt-1, AKT/PKB, Akt/PKB, AKT1, Akt1, akt1, ATAKT1, CG4006, CWS6, D-Akt, DAkt, Dakt, dAKT, dAkt, dakt, dAKT/dPKB, dAkt/PKB, DAKT1, DAkt1, Dakt1, dAKT1, dAkt1, dakt1, DAKT1/PKB, Dmel\\CG4006, DPKB, Dpkb, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, pkb, PKB-ALPHA, PKB/Akt, PKB/AKT, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, RAC, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xActProtein level used designations for AKT1
- PKB alpha
- RAC-PK-alpha
- RAC-alpha serine/threonine-protein kinase
- protein kinase B alpha
- proto-oncogene c-Akt
- rac protein kinase alpha
- AKT1 kinase
- protein kinase B-alpha
- proto-oncogene c-AKT
- related to A and C kinases
- Akt kinase
- Akt1-PA
- Akt1-PB
- Akt1-PC
- CG4006-PA
- CG4006-PB
- CG4006-PC
- dAkt kinase
- protein kinase B
- related to PKA to PKC protein kinases
- related to the A and C kinases
- actin, cytoplasmic 1
- beta-actin
- gamma non-muscle actin
- RAC protein kinase alpha RAC-PK alpha
- murine thymoma viral (v-akt) oncogene homolog 1
- thymoma viral proto-oncogene 1
- v-akt murine thymoma viral oncogene-like protein 1
- serine/threonine protein kinase
- Akt
- protein kinase Akt-1
- protein kinase B, alpha
- xAkt
- v-akt murine thymoma viral oncogene homolog 1
- v-akt murine thymoma viral oncogene-like 1
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