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AKR1D1 产品

(Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

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The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010].

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Featured AKR1D1 Categories

AKR1D1 抗体

High quality antibodies with extensive validation data.

AKR1D1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AKR1D1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
Cat. No. ABIN562993
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7235767
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7142330
Quantity 100 μg
Datasheet Datasheet

Recommended AKR1D1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234515
Quantity 96 tests
Datasheet Datasheet

Recommended AKR1D1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1344768
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121785
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344770
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our AKR1D1 Products

Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).

Chaudhry, Thirumaran, Yasuda, Yang, Fan, Strom, Schuetz: "Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 8, pp. 1538-47, (2013) (PubMed).

Synonyms and alternative names related to AKR1D1

3-oxo-5-beta-steroid 4-dehydrogenase-like (LOC491379), aldo-keto reductase family 1 member D1 (AKR1D1), aldo-keto reductase family 1, member D1 (Akr1d1), aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) (AKR1D1), 3o5bred, CBAS2, SRD5B1

Protein level used designations for AKR1D1

  • 3-oxo-5-beta-steroid 4-dehydrogenase
  • delta 4-3-ketosteroid-5-beta-reductase
  • delta(4)-3-ketosteroid 5-beta-reductase
  • delta(4)-3-oxosteroid 5-beta-reductase
  • steroid-5-beta-reductase, beta polypeptide 1 (3-oxo-5 beta-steroid delta 4-dehydrogenase beta 1)
  • aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
  • aldo-keto reductase family 1 member D1
  • delta4-3-oxosteroid 5beta-reductase
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