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AKAP12 产品

(A Kinase (PRKA) Anchor Protein 12 (AKAP12))

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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured AKAP12 Categories

AKAP12 抗体

High quality antibodies with extensive validation data.

AKAP12 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended AKAP12 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7443371
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro), FACS, IF (cc), IF (p)
Validations
  • (3)
Cat. No. ABIN685732
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN564142
Quantity 100 μg
Datasheet Datasheet

Recommended AKAP12 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964513
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN770578
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN778155
Quantity 96 tests
Datasheet Datasheet

Recommended AKAP12 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344712
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416580
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AKAP12 Products

Bateman, Jaworski, Ao, Wang, Litzi, Dubil, Marcus, Conrads, Teng, Hood, Phippen, Vasicek, McGuire, Paz, Sidransky, Hamilton, Maxwell, Darcy, Conrads: "Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients." in: Journal of proteome research, Vol. 14, Issue 4, pp. 1900-10, (2015) (PubMed).

Lin, Tan, Lim, Khoo, Lim, Chung: "iTRAQ analysis of colorectal cancer cell lines suggests Drebrin (DBN1) is overexpressed during liver metastasis." in: Proteomics, Vol. 14, Issue 11, pp. 1434-43, (2014) (PubMed).

Soloff, Jeng, Izban, Sinha, Luxon, Stamnes, England: "Effects of progesterone treatment on expression of genes involved in uterine quiescence." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 18, Issue 8, pp. 781-97, (2011) (PubMed).

Mardin, Petrov, Enns, Senninger, Haier, Mees: "SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma." in: BMC cancer, Vol. 10, pp. 549, (2010) (PubMed).

Tan, Tan, Lin, Lim, Hew, Chung: "Quantitative and temporal proteome analysis of butyrate-treated colorectal cancer cells." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 6, pp. 1174-85, (2008) (PubMed).

Siegel, Grove, Carr: "SSeCKS immunolabeling in rat primary sensory neurons." in: Brain research, Vol. 926, Issue 1-2, pp. 126-36, (2002) (PubMed).

Nauert, Klauck, Langeberg, Scott: "Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein." in: Current biology : CB, Vol. 7, Issue 1, pp. 52-62, (1997) (PubMed).

Synonyms and alternative names related to AKAP12

A kinase (PRKA) anchor protein 12b (akap12b), A-kinase anchoring protein 12 (AKAP12), A kinase (PRKA) anchor protein (gravin) 12 (Akap12), A-kinase anchoring protein 12 (Akap12), AI317366, akap12, AKAP12, AKAP12A, AKAP12B, AKAP12G, AKAP250, cb27, esr1, fb72g12, id:ibd1202, sb:cb27, si:ch73-192g21.1, Srcs5, SSeCKS, Tsga12, wu:fb72g12, wu:fc21c03

Protein level used designations for AKAP12

  • A kinase (PRKA) anchor protein (gravin) 12
  • A-kinase anchor protein 12
  • gravin
  • A kinase (PRKA) anchor protein 12
  • A kinase anchor protein 12
  • A-kinase anchor protein 12-like
  • a-kinase anchor protein 12-like
  • AKAP-12
  • gercelin
  • germ cell lineage protein gercelin
  • src-suppressed C kinase substrate
  • testis specific gene A12
  • v-src suppressed transcript 5
  • SSeCKS, Gravin, AKAP250
  • A-kinase anchor protein, 250kDa
  • AKAP 250
  • Src-Suppressed C Kinase Substrate
  • kinase scaffold protein gravin
  • myasthenia gravis autoantigen gravin
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