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AHCY 产品

(Adenosylhomocysteinase (AHCY))

Categories

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].

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Featured AHCY Categories

AHCY 抗体

High quality antibodies with extensive validation data.

AHCY ELISA试剂盒

Reliable ELISA kits for a wide range of species.

AHCY 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AHCY 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN559816
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN513193
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN7101497
Quantity 20 μL
Datasheet Datasheet

Recommended AHCY ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964630
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964629
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953489
Quantity 96 tests
Datasheet Datasheet

Recommended AHCY 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121712
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121711
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344622
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our AHCY Products

Fling, Doskey, Fader, Nault, Zacharewski: "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice." in: Scientific reports, Vol. 10, Issue 1, pp. 14831, (2021) (PubMed).

Huang, Huan, Liu: "A comparative proteomic analysis reveals important proteins for the fertilization and early embryonic development of the oyster Crassostrea gigas." in: Proteomics, Vol. 17, Issue 1-2, (2016) (PubMed).

Chayka, DAcunto, Middleton, Arab, Sala: "Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells." in: The Journal of biological chemistry, Vol. 290, Issue 4, pp. 2198-212, (2015) (PubMed).

Fernandez-Sanchez, Gonatopoulos-Pournatzis, Preston, Lawlor, Cowling: "S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation." in: Molecular and cellular biology, Vol. 29, Issue 23, pp. 6182-91, (2009) (PubMed).

Kim, Kang, Lee, Lee, Yu, Kim, Lee: "Identification of S100A8 and S100A9 as serological markers for colorectal cancer." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1368-79, (2009) (PubMed).

Li, Cai, Fang, Borchardt, Kuczera, Middaugh, Schowen: "Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 2. The role of helix 18 stability." in: Biochemistry, Vol. 47, Issue 17, pp. 4983-91, (2008) (PubMed).

Yideng, Jianzhong, Ying, Juan, Jinge, Shenglan, Xiaoqun, Shuren: "Homocysteine-mediated expression of SAHH, DNMTs, MBD2, and DNA hypomethylation potential pathogenic mechanism in VSMCs." in: DNA and cell biology, Vol. 26, Issue 8, pp. 603-11, (2007) (PubMed).

Yuan, Borchardt: "Photoaffinity labeling of human placental S-adenosylhomocysteine hydrolase with [2-3H]8-azido-adenosine." in: The Journal of biological chemistry, Vol. 270, Issue 27, pp. 16140-6, (1995) (PubMed).

Synonyms and alternative names related to AHCY

adenosylhomocysteinase (AHCY), adenosylhomocysteinase (ahcy), adenosylhomocysteinase (ahcY), Adenosylhomocysteinase (ahcY), adenosylhomocysteinase (MMAH_RS02605), adenosylhomocysteinase (Srot_2217), adenosylhomocysteinase (Ndas_3755), adenosylhomocysteinase (Deba_0936), adenosylhomocysteinase (Palpr_2392), adenosylhomocysteinase (Calni_0569), adenosylhomocysteinase (LOC100282150), adenosylhomocysteinase (Intca_2510), adenosylhomocysteinase (Marky_0392), adenosylhomocysteinase (Desac_1394), S-adenosylhomocysteine hydrolase (Tc00.1047053511229.50), S-adenosylhomocysteine hydrolase (Tc00.1047053511589.200), S-adenosylhomocysteine hydrolase (Tb11.01.1350), S-adenosylhomocysteine hydrolase (LMJF_36_3910), S-adenosylhomocysteine hydrolase (MCYG_06244), S-adenosylhomocysteine hydrolase (Ahcy), adenosylhomocysteinase (Ahcy), adenosylhomocysteinase S homeolog (ahcy.S), AA987153, adoHcyase, Ahcy, ahcy, AL024110, cb1079, CuBP, D150, hm:zeh1173, hm:zeh1364, PSPTO5068, sahh, SAHH, wu:fj67b02

Protein level used designations for AHCY

  • S-adenosylhomocysteine hydrolase
  • adenosylhomocysteinase
  • Adenosylhomocysteinase
  • adenosylhomocysteinase-like
  • S-adenosyl-L-homocysteine hydrolase
  • adoHcyase
  • S-adenosyl-L-homocysteine hydrolase B
  • adenosylhomocysteinase B
  • adoHcyase B
  • liver copper-binding protein
  • dtp
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