Afadin 产品
(Afadin (MLLT4))
Categories
This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6\;11)(q27\;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011].
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Featured Afadin Categories
Afadin 抗体
High quality antibodies with extensive validation data.
Recommended Afadin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7143570
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Human, Monkey, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN204949
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Drosophila melanogaster, Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN925787
Quantity
100 μg
Datasheet
Datasheet
Recommended Afadin 蛋白
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Reactivity
Source
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Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN5777013
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Afadin Products
: "Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation." in: Nature structural & molecular biology, Vol. 23, Issue 2, pp. 155-63, (2016) (PubMed).: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, (2004) (PubMed).
: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).
: "Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin." in: The Journal of cell biology, Vol. 147, Issue 7, pp. 1569-82, (2000) (PubMed).
: "Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1." in: The Journal of biological chemistry, Vol. 275, Issue 36, pp. 27979-88, (2000) (PubMed).
: "The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain." in: The Journal of cell biology, Vol. 144, Issue 2, pp. 361-71, (1999) (PubMed).
: "Identification of AF-6 and canoe as putative targets for Ras." in: The Journal of biological chemistry, Vol. 271, Issue 2, pp. 607-10, (1996) (PubMed).
: "Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation." in: Cancer research, Vol. 53, Issue 23, pp. 5624-8, (1994) (PubMed).
Synonyms and alternative names related to Afadin
afadin, adherens junction formation factor (AFDN), afadin, adherens junction formation factor L homeolog (afdn.L), afadin, adherens junction formation factor a (afdna), afadin (LOC589923), afadin (LOC100177180), afadin, adherens junction formation factor (afdn), afadin, adherens junction formation factor (Afdn), 5033403D15Rik, af-6, Af-6, af6, AF6, Af6, Afadin, Gm314, I-afadin, MLLT4, RP3-431P23.3, S-afadin, si:ch211-278j12.1Protein level used designations for Afadin
- myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
- afadin-like
- ALL1-fused gene from chromosome 6 protein
- afadin
- protein AF-6
- myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog
- protein Af-6
- myeloid/lymphoid or mixed-lineage leukemia 4
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