Adenylosuccinate Lyase 产品
(Adenylosuccinate Lyase (ADSL))
Categories
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Adenylosuccinate Lyase Categories
Adenylosuccinate Lyase 抗体
High quality antibodies with extensive validation data.
Adenylosuccinate Lyase ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Adenylosuccinate Lyase 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Adenylosuccinate Lyase 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7143352
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN7262084
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN947541
Quantity
100 μg
Datasheet
Datasheet
Recommended Adenylosuccinate Lyase ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964640
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1120655
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1120652
Quantity
96 tests
Datasheet
Datasheet
Recommended Adenylosuccinate Lyase 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1344500
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121722
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7504226
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Adenylosuccinate Lyase Products
: "Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts." in: PLoS ONE, Vol. 9, Issue 6, pp. e100077, (2014) (PubMed).: "Modulation of de novo purine biosynthesis leads to activation of AMPK and results in improved glucose handling and insulin sensitivity." in: Journal of diabetes and metabolic disorders, Vol. 13, pp. 51, (2014) (PubMed).
: "Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency." in: Human molecular genetics, Vol. 21, Issue 7, pp. 1534-43, (2012) (PubMed).
: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).
: "The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 20, pp. 8034-42, (2001) (PubMed).
: "Abnormal expression and subcellular distribution of subunit proteins of the AP-3 adaptor complex lead to platelet storage pool deficiency in the pearl mouse." in: Blood, Vol. 94, Issue 1, pp. 146-55, (1999) (PubMed).
: "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet." in: The EMBO journal, Vol. 16, Issue 15, pp. 4508-18, (1997) (PubMed).
Synonyms and alternative names related to Adenylosuccinate Lyase
adenylosuccinate lyase (ADSL), adenylosuccinate lyase (adsl), adenylosuccinate lyase L homeolog (adsl.L), adenylosuccinate lyase (ASL), adenylosuccinate lyase (purB), adenylosuccinase; ASL (purB), adenylosuccinate lyase (purB,adsL), adenylosuccinate lyase (Mrub_2293), adenylosuccinate lyase (MMAH_RS02975), adenylosuccinate lyase (Arnit_0089), adenylosuccinate lyase (Mesil_1058), adenylosuccinate lyase (Slip_0597), adenylosuccinate lyase (Trad_2452), adenylosuccinate lyase (Deba_0652), adenylosuccinate lyase (Toce_1174), Adenylosuccinate lyase (Acear_2324), Adenylosuccinate lyase (Igag_0272), adenylosuccinate lyase (Saut_2156), Adenylosuccinate lyase (Fbal_1996), adenylosuccinate lyase (Ndas_2434), adenylosuccinate lyase (Ilyop_0196), adenylosuccinate lyase (Lbys_2961), adenylosuccinate lyase (MFER_RS02920), adenylosuccinate lyase (Palpr_2192), adenylosuccinate lyase (Calni_0061), adenylosuccinate lyase (Ftrac_3746), L-Aspartase-like family protein (AT1G36280), Adenylosuccinate lyase (Olsu_1764), adenylosuccinate lyase (Adsl), Adl, adsL, AMPS, ASASE, ASL, Asl, F15C21.8, F15C21_8, fi60b04, MGC53383, MGC69239, purB, wu:fi60b04, zgc:56061Protein level used designations for Adenylosuccinate Lyase
- adenylosuccinate lyase
- Adenylosuccinate lyase
- adenylosuccinate lyase-like
- adenylosuccinase
- ASase
- adenylosuccinate lyase 1
- test
- ASL
- adenysuccinate lyase
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