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ADD2 ELISA试剂盒

(Adducin 2 (Beta) (ADD2))

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010].

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ADD2 ELISA 试剂盒 (ABIN1380906)

ADD2 适用: 人, 小鼠, 大鼠 Colorimetric Cell ELISA Cell Culture Cells

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Popular ADD2 ELISA试剂盒

Product

Reactivity

Analytical Method

Validations

Cat. No.

Quantity

Datasheet

ADD2 ELISA 试剂盒

Reactivity Human, Mouse, Rat

Analytical Method Qualitative Cell ELISA

Validations

Cat. No. ABIN1380906

Quantity 96 tests

Datasheet Datasheet

Aliases for ADD2 ELISA试剂盒

adducin 2 (ADD2) ELISA试剂盒
adducin 2 (beta) (add2) ELISA试剂盒
adducin 2 (add2) ELISA试剂盒
adducin 2 (beta) (Add2) ELISA试剂盒
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