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ADAR 产品

(Adenosine Deaminase, RNA-Specific (ADAR))

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This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010].

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Featured ADAR Categories

ADAR 抗体

High quality antibodies with extensive validation data.

ADAR ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ADAR 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ADAR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN513112
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (10)
Cat. No. ABIN6136553
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (5)
Cat. No. ABIN947535
Quantity 100 μL
Datasheet Datasheet

Recommended ADAR ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6211695
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN2870404
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN2870406
Quantity 96 tests
Datasheet Datasheet

Recommended ADAR 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305925
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
  • (1)
Cat. No. ABIN1095574
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092239
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ADAR Products

Chen, Chen, Su, Chin, Chen, Liou, Chen, Chang, Huang, Wang, Wang, Chang, Lin, Zheng, Lin, Hsiao: "Genome-wide gene expression array identifies novel genes related to disease severity and excessive daytime sleepiness in patients with obstructive sleep apnea." in: PLoS ONE, Vol. 12, Issue 5, pp. e0176575, (2017) (PubMed).

Orecchini, Doria, Antonioni, Galardi, Ciafrè, Frassinelli, Mancone, Montaldo, Tripodi, Michienzi: "ADAR1 restricts LINE-1 retrotransposition." in: Nucleic acids research, Vol. 45, Issue 1, pp. 155-168, (2016) (PubMed).

Yang, Hu, Lin, Han, Zhu, Tan, Ye, Wang, Wu, Yin, Bao, Jiang, Yuan, Qiang, Peng: "PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas." in: Cellular and molecular life sciences : CMLS, Vol. 72, Issue 22, pp. 4383-97, (2015) (PubMed).

Liu, Chen, Yeh, Li, Wu, Chen, Chen, Yeh: "ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers." in: PLoS ONE, Vol. 8, Issue 12, pp. e81922, (2014) (PubMed).

Liu, Wang, Wu, Cao, Tang, Xing, Ma, Zhang, Luo: "Five novel mutations in the ADAR1 gene associated with dyschromatosis symmetrica hereditaria." in: BMC medical genetics, Vol. 15, pp. 69, (2014) (PubMed).

Chen, Li, Lin, Chan, Chow, Song, Liu, Yuan, Fu, Kong, Qi, Li, Zhang, Tong, Kwong, Man, Lo, Lok, Tenen, Guan: "Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma." in: Nature medicine, Vol. 19, Issue 2, pp. 209-16, (2013) (PubMed).

Ben-Zvi, Amariglio, Paret, Nevo-Caspi: "F11R expression upon hypoxia is regulated by RNA editing." in: PLoS ONE, Vol. 8, Issue 10, pp. e77702, (2013) (PubMed).

Pan, Ye, Franco, Li, Yu, Zou, Zhang, Jiao, Lin: "Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study." in: Journal of affective disorders, Vol. 109, Issue 1-2, pp. 75-82, (2008) (PubMed).

Li, Yang, Shi, Huang: "A novel missense mutation in DSRAD in a family with dyschromatosis symmetrica hereditaria." in: Archives of dermatological research, Vol. 299, Issue 5-6, pp. 273-5, (2007) (PubMed).

Lykke-Andersen, Piñol-Roma, Kjems: "Alternative splicing of the ADAR1 transcript in a region that functions either as a 5'-UTR or an ORF." in: RNA (New York, N.Y.), Vol. 13, Issue 10, pp. 1732-44, (2007) (PubMed).

Synonyms and alternative names related to ADAR

adenosine deaminase, RNA-specific (adar), adenosine deaminase, RNA-specific S homeolog (adar.S), adenosine deaminase, RNA specific (ADAR), Adenosine deaminase acting on RNA (Adar), adenosine deaminase acting on RNA (Adar), adenosine deaminase acting on RNA (CpipJ_CPIJ011849), double-stranded RNA-specific editase 1 (LOC100114127), adenosine deaminase, RNA-specific (Adar), ADAR, adar, adar1, ADAR1, Adar1, adr, AGS6, AV242451, CG12598, cg12598, dADAR, dAdar, Dmel\\CG12598, drada, DRADA, DSH, dsRAD, DSRAD, dsRAD-1, EG:BACN35H14.1, G1P1, hypnos-2, IFI-4, IFI4, K88DSRBP, mZaADAR, NV18763, P136, red1, wu:fc22a02

Protein level used designations for ADAR

  • double-stranded RNA-specific adenosine deaminase
  • dsRNA adenosine deaminase
  • adenosine deaminase, RNA-specific
  • RNA-specific adenosine deaminase
  • Adar-PA
  • Adar-PB
  • Adar-PC
  • Adar-PD
  • Adar-PE
  • Adar-PF
  • Adar-PH
  • Adar-PI
  • Adar-PJ
  • Adar-PK
  • Adar-PL
  • Adar-PM
  • CG12598-PA
  • CG12598-PB
  • CG12598-PC
  • CG12598-PD
  • CG12598-PE
  • CG12598-PF
  • CG12598-PH
  • CG12598-PI
  • CG12598-PJ
  • CG12598-PK
  • CG12598-PL
  • CG12598-PM
  • adenosine deaminase acting on RNA
  • adenosine deaminases acting on RNA
  • hypoxia, anoxia, sensitive 2
  • DRADA
  • 136 kDa double-stranded RNA-binding protein
  • adenosine deaminase acting on RNA 1-A
  • interferon-induced protein 4
  • interferon-inducible protein 4
  • RNA adenosine deaminase 1
  • RNA-specific adenosine deaminase p110 form
  • RNA-specific adenosine deaminase p150 form
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