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ADAM15 产品

(ADAM Metallopeptidase Domain 15 (ADAM15))

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The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Featured ADAM15 Categories

ADAM15 抗体

High quality antibodies with extensive validation data.

ADAM15 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ADAM15 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ADAM15 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN7265434
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN961131
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN2855098
Quantity 100 μL
Datasheet Datasheet

Recommended ADAM15 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953447
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN5510655
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730565
Quantity 96 tests
Datasheet Datasheet

Recommended ADAM15 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305849
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305851
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320075
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ADAM15 Products

Chatterjee, Beard, Reynolds, Haines, Guo, Rubin, Guido, Wu, Yuan: "MicroRNA-147b regulates vascular endothelial barrier function by targeting ADAM15 expression." in: PLoS ONE, Vol. 9, Issue 10, pp. e110286, (2014) (PubMed).

Ungerer, Doberstein, Bürger, Hardt, Boehncke, Böhm, Pfeilschifter, Dummer, Mihic-Probst, Gutwein: "ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma." in: Biochemical and biophysical research communications, Vol. 401, Issue 3, pp. 363-9, (2010) (PubMed).

Böhm, Aigner, Roy, Brodie, Blobel, Burkhardt: "Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling." in: Arthritis and rheumatism, Vol. 52, Issue 4, pp. 1100-9, (2005) (PubMed).

Synonyms and alternative names related to ADAM15

ADAM metallopeptidase domain 15 (ADAM15), ADAM metallopeptidase domain 15 L homeolog (adam15.L), ADAM metallopeptidase domain 15 (adam15), a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15), ADAM metallopeptidase domain 15 (Adam15), ADAM15, mdc15, MDC15, metargidin, tMDCVI

Protein level used designations for ADAM15

  • ADAM metallopeptidase domain 15
  • a disintegrin and metalloproteinase domain 15
  • metalloproteinase ADAM15
  • disintegrin and metalloproteinase domain-containing protein 15-like
  • AD56
  • ADAM 15
  • MDC-15
  • a disintegrin and metalloprotease domain 15 (metargidin)
  • a disintegrin and metalloproteinase domain 15 (metargidin)
  • disintegrin and metalloprotease 15
  • disintegrin and metalloproteinase domain-containing protein 15
  • metalloprotease RGD disintegrin protein
  • metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15
  • CRII-7
  • a disintegrin and metallopeptidase domain 15 (metargidin)
  • metargidin
  • tMDC VI
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