ACVR2A 产品
(Activin A Receptor, Type IIA (ACVR2A))
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This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. [provided by RefSeq, Jul 2008].
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Featured ACVR2A Categories
ACVR2A 抗体
High quality antibodies with extensive validation data.
ACVR2A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ACVR2A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACVR2A 抗体
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Application
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Cat. No.
ABIN7438676
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF
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- (6)
Cat. No.
ABIN3015792
Quantity
100 μL
Datasheet
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Reactivity
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Application
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- (5)
Cat. No.
ABIN7427552
Quantity
100 μL
Datasheet
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Recommended ACVR2A ELISA试剂盒
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Cat. No.
ABIN6953429
Quantity
96 tests
Datasheet
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Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964578
Quantity
96 tests
Datasheet
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Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1120350
Quantity
96 tests
Datasheet
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Recommended ACVR2A 蛋白
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Source
Baculovirus infected Insect Cells
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Cat. No.
ABIN5854601
Quantity
50 μg
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Reactivity
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Wheat germ
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Cat. No.
ABIN1305813
Quantity
10 μg
Datasheet
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Reactivity
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ABIN1305811
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Latest Publications for our ACVR2A Products
: "ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells." in: Haematologica, Vol. 104, Issue 3, pp. 533-545, (2019) (PubMed).: "A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6001-6010, (2019) (PubMed).
: "Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." in: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).
: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).
: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." in: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).
: "Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers." in: Gastroenterology, Vol. 126, Issue 3, pp. 654-9, (2004) (PubMed).
: "Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 12, pp. 1867-71, (2003) (PubMed).
Synonyms and alternative names related to ACVR2A
activin A receptor type 2A (ACVR2A), activin A receptor type 2A (acvr2a), activin A receptor type 2A (Acvr2a), activin A receptor type 2A L homeolog (acvr2a.L), activin A receptor type 2Aa (acvr2aa), activin receptor IIA (Acvr2a), actr2a, actrii, ACTRII, ActrIIa, ACVR2, acvr2, Acvr2, ACVR2A, acvr2a, rActR-II, TactrII, wu:fa02e10, XSTK9Protein level used designations for ACVR2A
- activin receptor IIA
- activin receptor type-2A
- activin A receptor, type IIA
- ACTR-IIA
- activin receptor type IIA
- type II activin receptor
- activin A receptor, type II
- activin receptor, type IIA
- ACTRIIA
- activin receptor type II
- activin type 2 receptor
- activin receptor IIa
- etID22865.9
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