ACVR1C/ALK7 产品
(Activin Receptor Type 1C (ACVR1C))
Categories
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008].
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Featured ACVR1C/ALK7 Categories
ACVR1C/ALK7 抗体
High quality antibodies with extensive validation data.
ACVR1C/ALK7 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ACVR1C/ALK7 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACVR1C/ALK7 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN714596
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7143179
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Human, Pig
Application
IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1048286
Quantity
50 μg
Datasheet
Datasheet
Recommended ACVR1C/ALK7 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6226424
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385787
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN2747946
Quantity
96 tests
Datasheet
Datasheet
Recommended ACVR1C/ALK7 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN4369914
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305809
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7491395
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ACVR1C/ALK7 Products
: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).: "Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase ..." in: International journal of oncology, Vol. 49, Issue 5, pp. 1825-1838, (2017) (PubMed).
: "Overexpression of B2M and loss of ALK7 expression are associated with invasion, metastasis, and poor-prognosis of the pancreatic ductal adenocarcinoma." in: Cancer biomarkers : section A of Disease markers, Vol. 15, Issue 6, pp. 735-43, (2015) (PubMed).
: "ALK7 protects against pathological cardiac hypertrophy in mice." in: Cardiovascular research, Vol. 108, Issue 1, pp. 50-61, (2015) (PubMed).
: "Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28458-65, (2004) (PubMed).
: "Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31277-86, (2004) (PubMed).
: "Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta." in: Biology of reproduction, Vol. 68, Issue 5, pp. 1719-26, (2003) (PubMed).
Synonyms and alternative names related to ACVR1C/ALK7
activin A receptor type 1C (ACVR1C), activin A receptor, type IC (Acvr1c), activin A receptor type 1C (Acvr1c), ACVRLK7, Alk-7, ALK7, Alk7, C230097P10, habrec1Protein level used designations for ACVR1C/ALK7
- ACTR-IC
- ALK-7
- activin receptor type IC
- activin receptor type-1C
- activin receptor-like kinase 7
- TGF-beta type 1 receptor
- activin A receptor, type IC
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