ACVR1 抗体
(Activin Receptor Type I (ACRV1))
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008].
recommended
recommended
ACRV1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03507-03508 unconjugated
recommended
ACVR1 抗体 by Grade
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ACVR1 抗体 by 应用范围
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ACVR1 抗体 by 克隆形成能力
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ACVR1 抗体 by 克隆
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ACVR1 抗体 by 标记
Find ACVR1 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Latest Publications for our ACVR1 抗体
: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." in: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).
: "Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2." in: Biochemical and biophysical research communications, Vol. 455, Issue 3-4, pp. 347-52, (2014) (PubMed).
: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).
: "BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury." in: American journal of physiology. Renal physiology, Vol. 293, Issue 5, pp. F1641-8, (2007) (PubMed).
: "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva." in: Nature genetics, Vol. 38, Issue 5, pp. 525-7, (2006) (PubMed).
: "A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 9, pp. 3584-91, (2006) (PubMed).
: "EphB4 provides survival advantage to squamous cell carcinoma of the head and neck." in: International journal of cancer, Vol. 119, Issue 6, pp. 1236-48, (2006) (PubMed).
: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).
: "The distribution of activin and activin receptors in gestational tissues across human pregnancy and during labour." in: Placenta, Vol. 23, Issue 4, pp. 294-302, (2002) (PubMed).
Aliases for ACVR1 抗体
activin A receptor type 1 (ACVR1) 抗体activin A receptor type 1 (Acvr1) 抗体
activin A receptor, type 1 (Acvr1) 抗体
activin A receptor type 1 S homeolog (acvr1.S) 抗体
ActR-I 抗体
ActR-IA 抗体
ACTRI 抗体
actri 抗体
ActRIA 抗体
Acvr 抗体
acvr1 抗体
acvr1-a 抗体
acvr1-b 抗体
ACVR1A 抗体
acvr1a 抗体
ACVRLK2 抗体
Acvrlk2 抗体
acvrlk2 抗体
Alk-2 抗体
alk-2 抗体
ALK2 抗体
alk2 抗体
Alk8 抗体
alk8 抗体
D330013D15Rik 抗体
FOP 抗体
fop 抗体
sax 抗体
SKR1 抗体
skr1 抗体
Tsk7L 抗体
TSRI 抗体
tsri 抗体
xALK-2 抗体
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