Activin Receptor Type I 产品
(Activin Receptor Type I (ACRV1))
Categories
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008].
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Featured Activin Receptor Type I Categories
Activin Receptor Type I 抗体
High quality antibodies with extensive validation data.
Activin Receptor Type I ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Activin Receptor Type I 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Activin Receptor Type I 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, ICC, FACS
Validations
- (8)
Cat. No.
ABIN5611297
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5542584
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (4)
Cat. No.
ABIN392240
Quantity
400 μL
Datasheet
Datasheet
Recommended Activin Receptor Type I ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953435
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1747560
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Goat
Analytical Method
Validations
Cat. No.
ABIN1748783
Quantity
96 tests
Datasheet
Datasheet
Recommended Activin Receptor Type I 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305799
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7194131
Quantity
200 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7194135
Quantity
200 μg
Datasheet
Datasheet
Latest Publications for our Activin Receptor Type I Products
: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." in: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).
: "Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2." in: Biochemical and biophysical research communications, Vol. 455, Issue 3-4, pp. 347-52, (2014) (PubMed).
: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." in: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).
: "BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury." in: American journal of physiology. Renal physiology, Vol. 293, Issue 5, pp. F1641-8, (2007) (PubMed).
: "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva." in: Nature genetics, Vol. 38, Issue 5, pp. 525-7, (2006) (PubMed).
: "A limited set of human MicroRNA is deregulated in follicular thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 9, pp. 3584-91, (2006) (PubMed).
: "EphB4 provides survival advantage to squamous cell carcinoma of the head and neck." in: International journal of cancer, Vol. 119, Issue 6, pp. 1236-48, (2006) (PubMed).
: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).
: "The distribution of activin and activin receptors in gestational tissues across human pregnancy and during labour." in: Placenta, Vol. 23, Issue 4, pp. 294-302, (2002) (PubMed).
Synonyms and alternative names related to Activin Receptor Type I
activin A receptor type 1 (ACVR1), activin A receptor type 2B (ACVR2B), activin A receptor type 1 (Acvr1), activin A receptor, type 1 (Acvr1), activin A receptor type 1 S homeolog (acvr1.S), ActR-I, ActR-IA, ACTRI, actri, ActRIA, Acvr, acvr1, acvr1-a, acvr1-b, ACVR1A, acvr1a, ACVRLK2, Acvrlk2, acvrlk2, Alk-2, alk-2, ALK2, alk2, Alk8, alk8, D330013D15Rik, FOP, fop, sax, SKR1, skr1, Tsk7L, TSRI, tsri, xALK-2Protein level used designations for Activin Receptor Type I
- TGF-B superfamily receptor type I
- activin A receptor, type II-like kinase 2
- activin receptor type I
- activin receptor type-1
- activin receptor-like kinase 2
- hydroxyalkyl-protein kinase
- serine/threonine-protein kinase receptor R1
- ACTR-IIB
- activin receptor type IIB
- activin receptor type-2B
- testicular activin receptor IIB
- ACTR-I
- SKR1
- TSR-I
- activin A receptor, type 1
- activin type I receptor
- type I TGF B receptor
- activin A receptor, type I
- activin receptor type IA
- TSK-7L
- activin A receptor type 1 S homeolog
- activin A receptor type I S homeolog
- activin receptor like kinase-2
您还需要查找其他产品吗？
- Activin B
- Activin AB
- Activin A Receptor Type IB/ALK-4
- Activator of Basal Transcription 1
- Activating Transcription Factor 7
- Activated Protein C
- Activated Leukocyte Cell Adhesion Molecule
- Actin, Muscle Specific
- Actin, gamma 1
- Actin, Beta, gamma
- Actin, beta 2
- Actin, Alpha, gamma
- Actin, Alpha, Cardiac Muscle 1
- Actin, alpha 2, Smooth Muscle, Aorta
- Actin, alpha 1, Skeletal Muscle
- Actin-Related Protein 2
- Actin-Like 8
- Actin-Like 7A
- Actin-Like 6B
- Actin-Like 6A
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