ACTH 抗体
(Adrenocorticotropic hormone (ACTH))
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
ACTH 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
ACTH 抗体 by 适用
Find ACTH 抗体 for a variety of species such as anti-Human ACTH, anti-Rat ACTH, anti-Mouse ACTH. The species listed below are among those available. Click on a link to go to the corresponding products.
ACTH 抗体 by 抗体来源
Find ACTH 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
ACTH 抗体 by 抗原表位
Find ACTH 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
ACTH 抗体 by 克隆形成能力
Find available monoclonal or polyclonal ACTH 抗体. Click on a link to go to the corresponding products.
Popular ACTH 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
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Application
FACS, ELISA, ICC
Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
FACS, ELISA
Validations
- (4)
Cat. No.
ABIN7193599
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN668661
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
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Cat. No.
ABIN668676
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat, Vicia faba
Application
IF, ELISA, IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN2477253
Quantity
0.5 mL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB
Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
Validations
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Cat. No.
ABIN285004
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC
Validations
Cat. No.
ABIN1713643
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN668663
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN668678
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN873755
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN873758
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN873785
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN2809428
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN873756
Quantity
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Datasheet
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Latest Publications for our ACTH 抗体
: "Chemokine CXCL14-like immunoreactivity in the αMSH-producing cells and PRL-producing cells of the flat-tailed house gecko pituitary." in: The Journal of veterinary medical science, Vol. 82, Issue 4, pp. 408-413, (2020) (PubMed).: "Regulation of the corticosteroid signalling system in rainbow trout HPI axis during confinement stress." in: General and comparative endocrinology, Vol. 258, pp. 184-193, (2018) (PubMed).
: "Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder." in: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, Vol. 22, Issue 5, pp. 525-538, (2018) (PubMed).
: "Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat." in: Journal of neurochemistry, Vol. 128, Issue 5, pp. 776-86, (2014) (PubMed).
: "Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint stress in adult male rats." in: Brain research, Vol. 1529, pp. 74-82, (2013) (PubMed).
: "Anxiolytic effects and neuroanatomical targets of estrogen receptor-β (ERβ) activation by a selective ERβ agonist in female mice." in: Endocrinology, Vol. 153, Issue 2, pp. 837-46, (2012) (PubMed).
: "Dysregulation of the Hypothalamus-Pituitary-Adrenal Axis in Male and Female, Genetically Obese (ob/ob) Mice." in: Journal of neuroendocrinology, Vol. 4, Issue 6, pp. 765-71, (2011) (PubMed).
: "Estrogen impairs glucocorticoid dependent negative feedback on the hypothalamic-pituitary-adrenal axis via estrogen receptor alpha within the hypothalamus." in: Neuroscience, Vol. 159, Issue 2, pp. 883-95, (2009) (PubMed).
: "Recombinant rat and mouse growth hormones: risk assessment of carcinogenic potential in 2-year bioassays in rats and mice." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 97, Issue 2, pp. 548-61, (2007) (PubMed).
: "Cells of proopiomelanocortin lineage from the rodent anterior pituitary lack sexually dimorphic expression of neurofilaments." in: Neuroendocrinology, Vol. 83, Issue 5-6, pp. 360-70, (2006) (PubMed).
Aliases for ACTH 抗体
pro-opiomelanocortin-alpha (Pomc) 抗体proopiomelanocortin (POMC) 抗体
ACTH 抗体
alpha-MSH 抗体
alphaMSH 抗体
BE 抗体
Beta-LPH 抗体
beta-MSH 抗体
Clip 抗体
CLIP 抗体
Gamma-LPH 抗体
gamma-MSH 抗体
LPH 抗体
MSH 抗体
Npp 抗体
NPP 抗体
POC 抗体
Pomc-1 抗体
Pomc1 抗体
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