ABI1 抗体
(Abl-Interactor 1 (ABI1))
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10\;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011].
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Popular ABI1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (11)
Cat. No.
ABIN7436735
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN7265359
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN3043515
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7241930
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p), ICC
Validations
- (1)
- (3)
Cat. No.
ABIN3043678
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, FACS
Validations
- (4)
Cat. No.
ABIN652475
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), FACS
Validations
- (4)
Cat. No.
ABIN4952702
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, FACS, EIA
Validations
- (4)
Cat. No.
ABIN453492
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, FACS
Validations
- (3)
Cat. No.
ABIN5647478
Quantity
0.08 mL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN3029824
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, IF/ICC
Validations
- (3)
Cat. No.
ABIN3003792
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Hamster, Human, Mouse
Application
WB, IP, IHC (p)
Validations
- (3)
Cat. No.
ABIN1449186
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Validations
- (1)
Cat. No.
ABIN675953
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Chicken, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6748109
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our ABI1 抗体
: "Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia." in: Stem cells and development, Vol. 26, Issue 9, pp. 656-677, (2017) (PubMed).: "AlphaII-spectrin participates in the surface expression of cell adhesion molecule L1 and neurite outgrowth." in: Experimental cell research, Vol. 322, Issue 2, pp. 365-80, (2014) (PubMed).
: "Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development." in: Developmental biology, Vol. 353, Issue 2, pp. 331-43, (2011) (PubMed).
: "Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma." in: Medical oncology (Northwood, London, England), Vol. 27, Issue 3, pp. 632-9, (2010) (PubMed).
: "Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21685-92, (2003) (PubMed).
: "Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease." in: Gene, Vol. 271, Issue 2, pp. 159-69, (2001) (PubMed).
: "Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases." in: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7591-601, (2000) (PubMed).
: "Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton." in: The Journal of biological chemistry, Vol. 273, Issue 22, pp. 13681-92, (1998) (PubMed).
: "ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23)." in: Blood, Vol. 92, Issue 4, pp. 1125-30, (1998) (PubMed).
: "Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth." in: Oncogene, Vol. 14, Issue 2, pp. 233-41, (1997) (PubMed).
Aliases for ABI1 抗体
abl interactor 1 (ABI1) 抗体abl-interactor 1 (Abi1) 抗体
abl-interactor 1a (abi1a) 抗体
abl interactor 1 S homeolog (abi1.S) 抗体
abl interactor 1 (abi1) 抗体
abl-interactor 1b (abi1b) 抗体
Abl-interactor 1 (Bm1_44660) 抗体
Abl interactor 1 (abi1) 抗体
abl-interactor 1 (LOAG_04356) 抗体
abl interactor 1 (Abi1) 抗体
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abi-1 抗体
abi1 抗体
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E3b1 抗体
e3b1 抗体
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ssh3bp 抗体
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