ABCG2 抗体
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
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ABCG2 抗体
High quality antibodies with extensive validation data.
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Latest Publications for our ABCG2 Products
: "Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats." in: Molecular neurobiology, Vol. 56, Issue 3, pp. 1921-1932, (2019) (PubMed).: "Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma." in: BMC cancer, Vol. 17, Issue 1, pp. 156, (2018) (PubMed).
: "Localization of the placental BCRP/ABCG2 transporter to lipid rafts: Role for cholesterol in mediating efflux activity." in: Placenta, Vol. 55, pp. 29-36, (2018) (PubMed).
: "Characteristics of doxorubicin-selected multidrug-resistant human leukemia HL-60 cells with tolerance to arsenic trioxide and contribution of leukemia stem cells." in: Oncology letters, Vol. 15, Issue 1, pp. 1255-1262, (2018) (PubMed).
: "Cariprazine, A Dopamine D₂/D₃ Receptor Partial Agonist, Modulates ABCG2-Mediated Multidrug Resistance in Cancer." in: Cancers, Vol. 10, Issue 9, (2018) (PubMed).
: "Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol." in: Scientific reports, Vol. 8, Issue 1, pp. 587, (2018) (PubMed).
: "Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway." in: Biomedicine & pharmacotherapy, Vol. 107, pp. 793-805, (2018) (PubMed).
: "The dopamine D3 receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines." in: Cancer letters, Vol. 396, pp. 167-180, (2017) (PubMed).
: "Neurorescue by a ROS Decomposition Catalyst." in: ACS chemical neuroscience, Vol. 7, Issue 10, pp. 1374-1382, (2016) (PubMed).
: "Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors." in: Molecular pharmaceutics, Vol. 13, Issue 7, pp. 2507-23, (2016) (PubMed).
Synonyms and alternative names related to ABCG2
ATP binding cassette subfamily G member 2 (ABCG2), ATP binding cassette subfamily G member 2 (Junior blood group) (abcg2), ATP binding cassette subfamily G member 2 (Junior blood group) (ABCG2), ATP binding cassette subfamily G member 2 (Junior blood group) L homeolog (abcg2.L), ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2), ATP binding cassette subfamily G member 2 (Junior blood group) (Abcg2), ATP-binding cassette sub-family G member 2 (LOC100008640), ATP binding cassette subfamily G member 2 (Abcg2), ABC15, ABCG2, ABCG3, ABCP, AI428558, bcrp, BCRP, BCRP1, Bcrp1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1Protein level used designations for ABCG2
- ATP-binding cassette, sub-family G, member 2
- breast cancer resistance protein
- ATP-binding cassette sub-family G member 2
- ATP-binding cassette transporter subfamily G member 2
- ATP-binding cassette, sub-family G (WHITE), member 2
- ATP-binding cassette sub-family G member 2-like
- ABC transporter
- ATP-binding cassette transporter G2
- mitoxantrone resistance-associated protein
- multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2
- placenta specific MDR protein
- placenta-specific ATP-binding cassette transporter
- ATP-binding cassette protein G2
- brain multidrug resistance protein
- ATP binding cassette superfamily G number 2 transporter
- breast cancer resistance protein 1 homolog
- mitoxantrone resistance protein 1
- ATP-binding cassette transporter sub-family G member 2
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