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ABCE1 抗体

RLI1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5708515
发货至: 中国
  • 抗原
    ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))
    适用
    人, 小鼠, 大鼠
    宿主
    克隆类型
    多克隆
    应用范围
    Western Blotting (WB)
    纯化方法
    Antigen affinity purified
    免疫原
    Amino acids K419-D599 from the human protein were used as the immunogen for the ABCE1 antibody.
    亚型
    IgG
  • 应用备注
    Western blot: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the ABCE1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))
    别名
    ABCE1 / ATP binding cassette E1
    别名
    ATRLI1 antibody, RNAse l inhibitor protein 1 antibody, RNAse l inhibitor protein 1 antibody, ABCE1 antibody
    背景
    ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.
    UniProt
    P61221
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