ABCC5 产品
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
Categories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008].
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Featured ABCC5 Categories
ABCC5 抗体
High quality antibodies with extensive validation data.
ABCC5 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ABCC5 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ABCC5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (5)
Cat. No.
ABIN302162
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (3)
Cat. No.
ABIN6266184
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7160318
Quantity
100 μg
Datasheet
Datasheet
Recommended ABCC5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964517
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953382
Quantity
96 tests
Datasheet
Datasheet
Recommended ABCC5 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305459
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305461
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407949
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ABCC5 Products
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).: "Effects of chronic renal failure on brain drug transporters in rats." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 39-46, (2011) (PubMed).
: "Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ..." in: The American journal of pathology, Vol. 166, Issue 1, pp. 39-48, (2005) (PubMed).
Synonyms and alternative names related to ABCC5
ATP binding cassette subfamily C member 5 (ABCC5), ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5), ATP binding cassette subfamily C member 5 (Abcc5), ATP binding cassette subfamily C member 5 L homeolog (abcc5.L), 2900011L11Rik, ABC33, abc33, abcc5, Abcc5a, Abcc5b, AI132311, EST277145, MOAT-C, moat-c, MOATC, moatc, MRP5, Mrp5, mrp5, pABC11, pabc11, SMRP, smrpProtein level used designations for ABCC5
- ATP-binding cassette sub-family C member 5
- canalicular multispecific organic anion transporter C
- multi-specific organic anion transporter C
- multidrug resistance-associated protein 5
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5b
- ATP-binding cassette, sub-family C, member 5
- MOAT-C
- SMRP
- ATP-binding cassette sub-family C (CFTR/MRP) member 5a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- ATP binding cassette subfamily C member 5 L homeolog
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