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A2BP1 产品

(Ataxin 2-Binding Protein 1 (A2BP1))
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

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Featured A2BP1 Categories

A2BP1 抗体

High quality antibodies with extensive validation data.

A2BP1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

A2BP1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended A2BP1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7168273
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1929546
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN6254087
Quantity 100 μL
Datasheet Datasheet

Recommended A2BP1 ELISA试剂盒

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Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1156080
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1156081
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1156079
Quantity 96 tests
Datasheet Datasheet

Recommended A2BP1 蛋白

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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414183
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3087024
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3130115
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our A2BP1 Products

Elorza, Márquez, Cabrera, Sánchez-Trincado, Santos-Galindo, Hernández, Picó, Díaz-Hernández, García-Escudero, Irimia, Lucas: "Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors." in: Brain : a journal of neurology, (2021) (PubMed).

Gu, Bok, Yu, Caprioli, Piri: "Downregulation of splicing regulator RBFOX1 compromises visual depth perception." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200417, (2019) (PubMed).

Fogel, Wexler, Wahnich, Friedrich, Vijayendran, Gao, Parikshak, Konopka, Geschwind: "RBFOX1 regulates both splicing and transcriptional networks in human neuronal development." in: Human molecular genetics, Vol. 21, Issue 19, pp. 4171-86, (2012) (PubMed).

Terauchi, Peers, Kobayashi, Niyogi, Merchant: "Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis." in: Photosynthesis research, Vol. 105, Issue 1, pp. 39-49, (2010) (PubMed).

Synonyms and alternative names related to A2BP1

RNA binding protein, fox-1 homolog 1 (RBFOX1), RNA binding fox-1 homolog 1 (RBFOX1), RNA binding fox-1 homolog 1 (rbfox1), multicopper ferroxidase (FOX1), RNA binding protein, fox-1 homolog (C. elegans) 1 (Rbfox1), RNA binding protein, fox-1 homolog 1 (Rbfox1), 2BP1, A2bp, A2BP1, a2bp1, A2bp1, FOX-1, fox-1, fox1, FOX1, HRNBP1, Hrnbp1, zgc:103635

Protein level used designations for A2BP1

  • RNA binding protein, fox-1 homolog (C. elegans) 1
  • ataxin 2-binding protein 1
  • RNA binding protein fox-1 homolog 1
  • ataxin-2-binding protein 1
  • fox-1 homolog A
  • hexaribonucleotide-binding protein 1
  • ataxin 2 binding protein 1
  • hexaribonucleotide binding protein 1
  • RNA binding protein, fox-1 homolog 1
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