AANAT 产品
(Aralkylamine N-Acetyltransferase (AANAT))
Categories
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
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Featured AANAT Categories
AANAT 抗体
High quality antibodies with extensive validation data.
AANAT ELISA试剂盒
Reliable ELISA kits for a wide range of species.
AANAT 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AANAT 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat, Sheep
Application
ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (2)
- (6)
Cat. No.
ABIN751063
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, ICC, IP
Validations
- (2)
Cat. No.
ABIN7444538
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (2)
Cat. No.
ABIN7169324
Quantity
100 μg
Datasheet
Datasheet
Recommended AANAT ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965002
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965001
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953911
Quantity
96 tests
Datasheet
Datasheet
Recommended AANAT 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305403
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7395332
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7418458
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our AANAT Products
: "Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism." in: Reproductive biology and endocrinology : RB&E, Vol. 17, Issue 1, pp. 1, (2019) (PubMed).: "Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord." in: Journal of veterinary science, Vol. 15, Issue 3, pp. 335-42, (2016) (PubMed).
: "Arylalkylamine N-acetyltransferase: "the Timezyme"." in: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 4233-7, (2007) (PubMed).
: "14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles?" in: Journal of neuroendocrinology, Vol. 15, Issue 4, pp. 370-7, (2003) (PubMed).
: "Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase." in: Investigative ophthalmology & visual science, Vol. 43, Issue 2, pp. 564-72, (2002) (PubMed).
: "14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin." in: Biochemical Society transactions, Vol. 30, Issue 4, pp. 365-73, (2002) (PubMed).
: "Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87)." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 10, pp. 4699-706, (2002) (PubMed).
: "cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24097-107, (2001) (PubMed).
Synonyms and alternative names related to AANAT
aralkylamine N-acetyltransferase (AANAT), aralkylamine N-acetyltransferase (Aanat), arylalkylamine N-acetyltransferase (Aanat), AA-NAT, DSPS, Nat-2, Nat4, SNAT, SnatProtein level used designations for AANAT
- arylalkylamine N-acetyltransferase
- serotonin N-acetyltransferase
- serotonin acetylase
- Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase)
- Seretonin N-acetyltransferase
- arylakylamine N-acetyltransferase
- AA-NAT
- pineal serotonin N-acetyltransferase
- pineal arylalkylamine N-acetyltransferase
- aralkylamine N-acetyltransferase
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