14-3-3 sigma/SFN 产品
(Stratifin (SFN))
Categories
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
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Featured 14-3-3 sigma/SFN Categories
14-3-3 sigma/SFN 抗体
High quality antibodies with extensive validation data.
14-3-3 sigma/SFN ELISA试剂盒
Reliable ELISA kits for a wide range of species.
14-3-3 sigma/SFN 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended 14-3-3 sigma/SFN 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IP, IHC (p), ICC
Validations
- (1)
- (18)
Cat. No.
ABIN2854867
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN561091
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (6)
Cat. No.
ABIN185539
Quantity
100 μg
Datasheet
Datasheet
Recommended 14-3-3 sigma/SFN ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6959729
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970439
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1118667
Quantity
96 tests
Datasheet
Datasheet
Recommended 14-3-3 sigma/SFN 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319731
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319729
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399247
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our 14-3-3 sigma/SFN Products
: "UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3σ axis inhibits keratinocyte survival and proliferation." in: Oncotarget, Vol. 8, Issue 53, pp. 90674-90692, (2017) (PubMed).: "Comparative Tissue Proteomics of Microdissected Specimens Reveals Novel Candidate Biomarkers of Bladder Cancer." in: Molecular & cellular proteomics : MCP, (2015) (PubMed).
: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).
: "CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation." in: Genes & development, Vol. 29, Issue 21, pp. 2225-30, (2015) (PubMed).
: "Short-term type-1 diabetes differentially modulates 14-3-3 proteins in rat brain and liver." in: European journal of clinical investigation, Vol. 44, Issue 4, pp. 350-8, (2014) (PubMed).
: "An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 2, pp. e55493, (2013) (PubMed).
: "A Protein Epitope Signature Tag (PrEST) library allows SILAC-based absolute quantification and multiplexed determination of protein copy numbers in cell lines." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. O111.009613, (2012) (PubMed).
: "Differential gene expression profiling of primary cutaneous melanoma and sentinel lymph node metastases." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 25, Issue 6, pp. 828-37, (2012) (PubMed).
: "Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 82, Issue 10, pp. 670-5, (2008) (PubMed).
: "Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal." in: The Journal of biological chemistry, Vol. 283, Issue 13, pp. 8486-95, (2008) (PubMed).
Synonyms and alternative names related to 14-3-3 sigma/SFN
stratifin (SFN), stratifin (Sfn), Er, Mme1, YWHAS, YwhasProtein level used designations for 14-3-3 sigma/SFN
- 14-3-3 sigma
- 14-3-3 protein sigma
- epithelial cell marker protein 1
- 14-3-3 sigma protein
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, sigma polypeptide
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